The new formulation has a dispersible cherry flavor and contains the same amount of artemether and lumefantrine as the conventional tablet. – This randomized study examined 899 children, of whom 447 received the orodispersible tablet and 452 were traditional, crushed tablet given. More than 85 percent of patients in each treatment group completed the study, and 812 qualified for the final analysis. The day-28 cure rate was 97? 8 percent in the dispersible group and 98? 5 percent in the conventional group. The most common drug-related adverse event was vomiting, which occurred in 7 percent of the dispersible group and 9 percent of the conventional group.
Article The efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomized, single-blind, multicentre study Salim Abdulla, Issaka Sagara, Steffen Borrmann, Umberto D’Alessandro, Raquel Gonz? Mary Hamel, Bernard Ogutu, Andreas M rtensson?, John Lyimo, Hamma Maiga, Philip Sasi, Alain Nahum, Quique Bassat, Elizabeth Juma, Lucas Otieno, Anders Bj? Hans Peter Beck, Kim Andriano, Marc cousin, Gilbert Lef vre, David Ubben, Zulfikarali Premji the Lancet – DOI: 10.1016/S0140-6736 61492-0 Click here to view summary No No login required)..Dr John Newcomber, Department of Psychiatry, psychology and medical and this center for Clinical Trial, Washinton University School of Medicine, MO. Society of Women’s Health Research 1025 Connecticut Ave. 701 Washington.